Description
Pertuzumab/Trastuzumab (Phesgo) – Targeted Therapy for HER2-Positive Breast Cancer
Overview
Pertuzumab/Trastuzumab (Phesgo) is a prescription combination therapy for HER2-positive breast cancer. It contains two monoclonal antibodies—pertuzumab and trastuzumab—designed to block the HER2 receptor, a protein that promotes the growth of certain breast cancer cells. Phesgo is formulated as a fixed-dose subcutaneous injection, offering a faster, convenient alternative to intravenous infusion, while maintaining effective targeted therapy for early-stage and metastatic HER2-positive breast cancer.
Key Features / Indications
- Active Ingredients: Pertuzumab and Trastuzumab
- Therapeutic Class: Monoclonal Antibody / Targeted Therapy
- Indications:
o Early-stage HER2-positive breast cancer (adjuvant therapy)
o HER2-positive metastatic breast cancer
o Often administered with chemotherapy for enhanced effectiveness
- Administration: Subcutaneous injection under medical supervision
- Mechanism of Action: Dual HER2 blockade prevents cancer cell growth, promotes cell death, and reduces tumor progression
- Benefits:
o Combines two effective HER2-targeted therapies in a single injection
o Shorter administration time compared to intravenous therapy
o Improves patient convenience and adherence
o Enhances treatment outcomes in HER2-positive breast cancer
Why Choose Oncomed Pharmacy?
Oncomed Pharmacy provides authentic, high-quality Pertuzumab/Trastuzumab (Phesgo) with professional handling, storage, and guidance for safe administration. Our pharmacists support patients with dosing instructions, side-effect management, and ongoing care to ensure safe and effective therapy. Choosing Oncomed Pharmacy ensures reliable access to this advanced HER2-targeted therapy with dedicated patient support throughout treatment.
Uses of Medicine
Pertuzumab/Trastuzumab (Phesgo) is used for:
- Treating early-stage and metastatic HER2-positive breast cancer
- Blocking HER2 receptors to prevent cancer cell growth
- Supporting combination therapy with chemotherapy for improved outcomes
- Reducing tumor progression and improving patient survival
- Offering convenient subcutaneous administration for patient comfort










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